Professor Des Richardson
Development of Novel Agents that Target P-Glycoprotein Resistant Pancreatic Cancer
Grant
Development of Novel Agents that Target P-Glycoprotein Resistant Pancreatic Cancer
Award
2015 Innovation Grant
Institution
Principal Investigator
Professor Des Richardson, Professor of Cancer Cell Biology, NHMRC Senior Principal Research Fellow
Time required to complete project
1 year
Project Summary
Drug resistance is a major factor underlying the limited response of pancreatic cancer to chemotherapy. The project team’s drug design strategy is to target resistant pancreatic cancer by taking advantage of detoxifying P-glycoprotein pump to transport our drugs DIRECTLY to their sensitive site of action in the cancer cell (namely, the LYSOSOME).
Professor Des Richardson